Closed Limited Submissions

Slots: University of Southern California is invited to nominate 1 individual to apply

Deadlines

Internal Deadline: Friday, July 11th, 2025, 5pm PT Closed.

LOI: N/A

External Deadline: September 30, 2025, 5pm CT.

Award Information

Type: Grant

Estimated Number of Awards: Generally, fifteen new awards are granted annually and are activated on July 1 of the year of the competition.

Anticipated Amount: Grants are set at $300,000 for a three-year period with $100,000 payable in the first year and equal sums payable in the second and third years and are subject to the receipt of acceptable progress reports.

The awards are made to tax-exempt institutions described in section 501(c)(3) of the Internal Revenue Code and are designated for the support of the research described in the application.

Link: https://searlescholars.org/competition/award-information/

Who May Serve as PI: The Searle Scholars Scientific Advisory Board is primarily interested in the potential of applicants to make innovative and high-impact contributions to research over an extended period of time. 

Applicants for the 2026 competition (awards which will be activated on July 1, 2026) are expected to be pursuing independent research careers in biochemistry, cell biology, genetics, immunology, neuroscience, pharmacology, and related areas in chemistry, medicine, and the biological sciences. 

Applicants should have begun their appointment as an independent investigator at the assistant professor level on or after May 1, 2024. The appointment must be their first tenure-track position (or its nearest equivalent). 

Institutions which do not have tenure-track appointments should consult with the Scientific Director of the Program regarding eligibility of selected applicants PRIOR to nominating such individuals. 

The Searle Scholars Program does not ordinarily support purely clinical research but has supported research programs that include both clinical and basic components. Potential applicants who are unsure if their research is appropriate for our Program are encouraged to examine the research interests of present and former Searle Scholars on this website. 

Applicants who were nominated for awards in the previous competition year but were not awarded may still meet the eligibility criteria for the current competition. Institutions should consult with the Scientific Director of the Program regarding renomination of such individuals.

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://ris.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template

Materials to submit include:

• (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
• (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#, Gender, and Ethnicity. Please have this material prepared before beginning this application.

Purpose

The Searle Scholars Program is a limited submission award program that makes grants to selected academic and research institutions to support the independent research of outstanding early-career scientists who have recently been appointed as assistant professors on a tenure-track appointment. The Searle Scholars Program supports high risk, high reward research across a broad range of scientific disciplines.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.

Slots: 1.  Institutions may submit one proposal per session.

Deadlines

Internal Deadline: Monday, June 16th, 2025, 5pm PT Closed.

LOI: N/A

External Deadline: August 1, 2025

Award Information

Type: Grant

Estimated Number of Awards: N/A

Anticipated Amount: The grant provides $75,000 annually for a period of up to three years.  Grants are not renewable.  

Who May Serve as PI: The funds are designed to provide to tenure track faculty members in their first to fourth year, at American Institutions, who hold M.D. and/or Ph.D. degrees, start-up support to move the project forward to the point where R01 or other independent funding can be obtained.  Applicants with current R01 funding should not apply.

Link: https://emallinckrodtfoundation.org/guidelines

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://ris.usc.edu/oor-portal/. Use the template provided here:

RII-Limited-Submission-Application-Template.

Materials to submit include:

• (1) Two-Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
• (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#, Gender, and Ethnicity. Please have this material prepared before beginning this application.

Purpose

The Edward Mallinckrodt, Jr. Foundation supports early-stage biomedical investigators engaged in basic and translational research that has the potential to make fundamental advances in biomedical science.

As stated earlier, the funds are designed to provide to tenure track faculty members in their first to fourth year, at American Institutions, who hold M.D. and/or Ph.D. degrees, start-up support to move the project forward to the point where R01 or other independent funding can be obtained.  Applicants with current R01 funding should not apply.

Budgetary Requirements: The Foundation will not fund overhead. 

Slots: Universities/Institutions are limited to three applications per cycle.

One application per cycle per investigator.

Deadlines

Internal Deadline: Friday, July 18th, 2025, 5pm PT Closed.

Registration Deadline: Friday, September 19, 2025, 5pm PST

LOI: October 3rd, 2025, 5pm PST

Invited Proposals: December 12, 2025 5pm PST

Award Information

Award Type: Grant for basic science, ideally with potential translational applications

Award Amount: Up to $700,000 over three years. IDC cannot exceed 10%. 

Mathers considers the budget request with these factors in mind: the number of researchers and their training; the type of model being used for experiments (mouse, drosophila, c. elegans, etc.); supplies required for experiments; genetic sequencing or other outsourced services, test setup development, etc. The grant does not fund lab equipment.

Who May Serve as PI: Faculty.

Link to Award: http://www.mathersfoundation.org/

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://ris.usc.edu/oor-portal/. Use the template provided here:

RII-Limited-Submission-Application-Template.

Materials to submit include:

• (1) Two-Page Proposal Summary (1” margins; single-spaced; font type: Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
• (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.

Purpose/Additional Information:

• Examples of current research areas supported: immunology, microbiome, structural biology, cellular physiology, cancer biology, genetics, genomics, microbiology and infectious diseases, stem cell biology, and neuroscience. 
• Research areas NOT supported: Plant biology, oceanography, space exploration, global warming, medical imaging technology, and electrical engineering technology development, research conducted in human subjects, clinical trials, drug discovery.  
• Requests for funding previously federally supported research and/or applications pending federal approval will not be accorded priority consideration.
• Mathers reviewers look for innovative, novel proposals, which have scientific merit with an established published proof of concept, and which may not be fundable at the federal level.  

Slots: ADA will accept up to two (2) nominations per institution with one (1) nomination spanning basic through preclinical research and one (1) nomination spanning clinical through public health research. 

Each nomination can be for either of the Pathway Program Award types: Initiator or Accelerator. Please be aware that if an institution nominates two (2) applicants with proposed projects covering the same phase of research (i.e. basic through preclinical research studies), one of the submitted applications will be administratively disqualified from consideration for funding.

Deadlines

Internal Deadline: Friday, May 23rd, 2025Closed.

LOI: N/A

External Deadline: Wednesday, July 23rd, 2025

Award Information

Award Type: Grant

Anticipated Award Amount: Up to $100,000 year in Phase 1, up to $325,000/year in Phase 2. Applicants may request up to seven (7) years of combined funding support for phases one and two. The proposed project budget should not exceed the maximum total budget up to $1,625,000 USD.

Who May Serve as Applicant: Applicants must currently be in research training positions (i.e. post-doctoral fellowships, research fellowships) and can have no more than seven (7) years of training since their doctoral degree.

Initiator award recipients cannot concurrently hold an NIH K99/R00 grant. All other Career Development awards are allowable (unless holding of concurrent awards is prohibited by the other granting agency).

Candidate’s must hold a full-time appointment at their sponsoring institution. Rare exceptions to full- time positions may be granted on a case-by-case basis and must be pre-approved by ADA Research Programs staff prior to application submission.

Applicants must hold a MD, PhD, DMD, DO, PharmD, DVM or an equivalent health- or science-related degree.

Applicant fellowship positions must be at university-affiliated institutions or other non-profit research institutions within the United States and U.S. possessions.

To assure continued excellence and diversity among applicants and awardees, the Association welcomes applications from all qualified individuals and strongly encourages applications from persons with diverse backgrounds, including minority groups that are underrepresented in biomedical research.

Individuals must have permission to work within the U.S., either as U.S. citizens or permanent residents, or with appropriate work visas/permits. Institutional confirmation of permission to work within the U.S. will be required at the time of application submission.

Link to Award: https://professional.diabetes.org/research-grants/current-funding-opportunities-pathway-stop-diabetes

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://ris.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template

Materials to submit include:

• (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
• (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.

Purpose

The Pathway to Stop Diabetes® Initiator award is designed to support early career researchers who have distinguished themselves during their research training as exceptionally talented and promising research investigators with a high likelihood of establishing successful, independent research programs and making seminal contributions in diabetes research.

These awards are highly competitive and intended to support particularly innovative and transformational ideas that have the potential to have an exceptional impact in diabetes with an emphasis on the investigator’s potential to significantly transform diabetes through research (‘moving the needle’) to improve the lives of people with diabetes. These awards provide salary and research support for applicants during late stages of mentored training through establishment as independent research faculty.

If funded, the Principal Investigator must agree to devote at least 75% of their total time and overall effort towards research. This percentage includes time dedicated to the Association-funded grant in addition to grants supported by other funding agencies. Please note that during the award’s duration,

the Principal Investigator must commit between 75-100% effort towards the Association funded project in phase one and between 50-75% effort towards the Association funded project in phase two.

Initiator awards will provide two (2) distinct phases of research support. Applicants may request up to seven (7) years of combined funding support for phases one and two. The proposed project budget should not exceed the maximum total budget up to $1,625,000 USD.

• Phase One: During phase one, applicants may request up to $100,000 USD per year (including 10% indirect costs) for up to two (2) years for mentored research training to allow investigators to complete on-going research, publish results, receive additional training, and develop independent research plans.

Phase two support will be approved by the ADA Research Programs team contingent upon adequate progress in phase one, as well as the receipt and approval of documentation verifying that:

1. The candidate has obtained a faculty appointment at an accredited research institution.
   1. The institution has agreed to provide adequate laboratory space necessary to perform the proposed research and adequate time (75% effort) to dedicate to research.
   1. The institution provides the candidate with an adequate and protected start-up package.

Phase Two: During phase two, applicants may request up to $325,000 USD per year (including 30% indirect costs) for up to five (5) years to support independent research.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.